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5 Suppl ISBRA, May 2001, pp

L.ChenM.ZhangM

doi: 10.1167/iovs.66.14.41 67 JohnsIFrostGDornhorstA

Abstract Allosteric modulation of ligand-gated ion channels provides a powerful mechanism to fine-tune their activity without competing with endogenous ligands

3.3 Mechanistic target of the rapamycin Particularly, when ACSL4 was overexpressed, mTOR phosphorylation greatly increased, and when ACSL4 was downregulated, mTOR phosphorylation significantly decreased